Nexium (Esomeprazole)

drug information

Nexium (Esomeprazole) Drug Name

Nexium (Esomeprazole)

Drug Uses

Nexium decreases the amount of acid produced in the stomach. Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Nexium may also be given to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

How to use

Use Nexium as directed by your doctor.

  • Take Nexium by mouth with or without food.
  • Take it around the same time every day.
Ask your health care provider any questions you may have about how to use Nexium.



Drug Class and Mechanism

Nexium is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

Storage

Store Nexium at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Nexium out of the reach of children and away from pets.

Warnings/Precautions

Do not use Nexium if:

  • you are allergic to any ingredient in Nexium or to similar medicines (e.g., omeprazole);
  • you are taking an HIV protease inhibitor (e.g., atazanavir).
Contact your doctor or health care provider right away if any of these apply to you.

Important :
  • Nexium may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Nexium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds; or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
  • Nexium may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Esomeprazole.
  • Nexium should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
  • Nexium should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
  • If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nexium while you are pregnant. It is not known if Nexium is found in breast milk. Do not breast-feed while using Nexium.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

  • constipation; diarrhea; dry mouth; gas; headache; nausea; pain, swelling, or redness at the injection site; stomach pain.
Seek medical attention right away if any of these severe side effects occur:

  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); chest pain; fast heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; unusual bruising or bleeding; unusual tiredness.


More Information

Nexium is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

Nexium (Esomeprazole) - Video Information

video information

What is esomeprazole?

Esomeprazole decreases the amount of acid produced in the stomach.

Esomeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Esomeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Esomeprazole may also be given to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Esomeprazole may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about esomeprazole?

Do not use this medication if you are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox). Before taking this medication, tell your doctor if you have ever had liver disease or any type of heart disease. You may need a dose adjustment or special tests during treatment.

Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before your treatment is completed. Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

What should I discuss with my healthcare provider before taking esomeprazole?

Do not use this medication if you are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox). Before taking this medication, tell your doctor if you have ever had liver disease or any type of heart disease. You may need a dose adjustment or special tests during treatment.

Some conditions are treated with a combination of esomeprazole and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether esomeprazole passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take esomeprazole?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

This medicine is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.

Take each dose with a full glass (8 ounces) of water. Esomeprazole should be taken at least one hour before a meal. Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

You may open the delayed-release capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

Esomeprazole can be given through a nasogastric (NG) feeding tube. Open the capsule and sprinkle the medicine into a 60-milliliter syringe. Mix in 50 milliliters of water. Place the plunger into the syringe and shake the mixture well. Make sure there are no medicine granules stuck in the tip of the syringe. Attach the syringe to the NG tube and push the plunger down to empty the syringe into the tube. Then flush the tube with more water to wash the contents down.

It is important to use esomeprazole regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before your treatment is completed. Store esomeprazole at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, headache, drowsiness, blurred vision, fast heartbeat, nausea, dry mouth, sweating, flushing, shortness of breath, tremor, loss of coordination, or seizure (convulsions).

What should I avoid while taking esomeprazole?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using esomeprazole.

Esomeprazole side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may include:

  • headache;

  • diarrhea;

  • nausea, stomach pain, gas, constipation; or

  • dry mouth.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

What other drugs will affect esomeprazole?

Before taking esomeprazole, tell your doctor if you are using any of the following drugs:

  • atazanavir (Reyataz);

  • digoxin (Lanoxin, Lanoxicaps);

  • diazepam (Valium);

  • ketoconazole (Nizoral);

  • iron (Feosol, Mol-Iron, Fergon, Femiron, others); or

  • a blood thinner such as warfarin (Coumadin).

This list is not complete and there may be other drugs that can interact with esomeprazole. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about esomeprazole.
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